I would say it depends on the game you are wishing to run. I tend to use 1964, PJ64, PJ64k, Mupen64, Nemu64 and Corn. Out of them all the single best has to be the newest BETA of PJ64 1.7 along with its newest updates. Though I do still end up playing PJ64 1.5 with Glide64 Napalm for many games. That is more as its fast and I have a slower system.