Jabo's D3D6 1.5 is the most compatable plugin and should be your first port of call, but Glide64 is also very good with most games. Try these first, then try the others if a certain game does not run so well with these. Experiment!
This link (if it works) would give more details on game settings, and optimal plugins, for all plugin settings and games that are listed. If this link does not work it is in the General N64 Emulation Discussion section and called Game settings