Can a ROM be corrupted if the ROM is a good rom in the first place?

[FlotsamX]

I've gotten varied answers.

I'd think READ ONLY MEMORY would be self explanatory, but as said, I've gotten varied answers.

 

[Allnatural]

The file could become corrupted, after a nasty computer crash for instance. Happened to me once.

 

[FlotsamX]

What about something along the lines of cheats?

 

[Agozer]

Cheats only alter memory addresses while the game is running, not the actual ROM image in any way. What cheats can alter and mess up are battery saves and savestates.