I experience this problem with the following games: Doubutsu no Mori, Pokémon Snap, Majora's Mask, and Paper Mario. These are all games which use flash memory for saved games. Sometimes it saves correctly, but sometimes when I start up the game, my saved file is completely gone! Sometimes the file is still there, but not from the last time I saved. I am absolutely certain that this does not happen with non-flash games; I played through Banjo-Kazooie and most of Diddy Kong Racing and Super Mario 64 with no save problems. I can always use save states as a workaround, but this still bothers me a little...