still no, and romhacking is far to involved and the game itself would take forever to run.
Allow me to explain.
Lets use oot as an example:
Game size is 32MB in size (this is the size of the Good64 file there may be others larger or smaller)
The latest texture pack for this game is a little less then 1GB and when decompressed it exceedes 1GB of ram to load.
The N64 hardware was not ment to run anything that size and the largest rom for that system is 256MB i think.
This is not to say that there have been emulators modified for certain projects such as Supermario starroad but these mutant emulators are super buggy and are rejected by most of the emulation community.