Having same issue
Unhandled : R4300i Opcode:801F2208
Uknown: 05 06 02 D8 (Stopping Emulation)
Not the first time using emulations for Zelda, or any game for the matter.
I have successfully played the game WITH cheats on (not warp cheats, only item and health limits) up untill :
"After first entering the time realm, link becomes an adult. After listening to the prologues sheik requests that link goes to kakariko village to learn 'something new"
Everytime I enter kakariko village at night, or want to exit any time of day it gives me that error mentioned above.
Note I am using LEGEND OF ZELDA v1.0