I made all of my Final Fantasy VIII discs into ISOs using CloneCD and they all work except Disc 3. ePSXe opens the file and leaves me on a blank screen. I have tried ripping it twice and it still doesn't work yet running off the CD still works (but makes for horrific load times I don't want).

Does anybody have any solutions?

it may need you to load a patch

That sounds strange... Check the disk for scratches (obvious I know) and clean it. You might try a CD ROM emu for loading the ISO such as daemon tools at http://www.daemon-tools.net.

Yes! After making that weird daemon tools thing I now sort of have 2 CD-ROM drives and the FF8 Disc 3 one actually works!!!!

Thankyou so much Romboy :)