yopyop released a new "stable" version of desmume, ya can get the french version here:

yopyop156.ifrance.com

patchnotes:

Voila la version stable. L'ému ne devrait normalement plus se figer
(sauf bien sur, sur les demo voulant utiliser la 3Dfifo.

Here's the stable version. It shouldn't freez anymore.
(except of course, for demo that use 3Dfifo)